{"created":"2023-06-19T07:24:56.173688+00:00","id":318,"links":{},"metadata":{"_buckets":{"deposit":"7d9112f6-4aa6-478f-8c8f-b581b546a493"},"_deposit":{"created_by":3,"id":"318","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"318"},"status":"published"},"_oai":{"id":"oai:mpu.repo.nii.ac.jp:00000318","sets":["37:48:49"]},"author_link":["637","639","638","636","635","640"],"item_1_biblio_info_14":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"43","bibliographicPageStart":"33","bibliographicVolumeNumber":"5","bibliographic_titles":[{"bibliographic_title":"宮崎県立看護大学研究紀要"},{"bibliographic_title":"Journal of Miyazaki Prefectural Nursing University","bibliographic_titleLang":"en"}]}]},"item_1_creator_6":{"attribute_name":"著者名(日)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"今藤, さとみ"}],"nameIdentifiers":[{"nameIdentifier":"635","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須永, 清"}],"nameIdentifiers":[{"nameIdentifier":"636","nameIdentifierScheme":"WEKO"}]}]},"item_1_creator_7":{"attribute_name":"著者名よみ","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"イマフジ, サトミ"}],"nameIdentifiers":[{"nameIdentifier":"637","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"スナガ, キヨシ"}],"nameIdentifiers":[{"nameIdentifier":"638","nameIdentifierScheme":"WEKO"}]}]},"item_1_creator_8":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Imafuji, Satomi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"639","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sunaga, Kiyoshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"640","nameIdentifierScheme":"WEKO"}]}]},"item_1_description_1":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_1_description_11":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"正常妊娠前・妊娠中・分娩後の血中,尿中アミノ酸の量的,質的変化を検討した報告は多いが,帝王切開直後の尿中アミノ酸量を検討した報告はない。本研究では妊娠中,帝王切開後1週目,5週目及び10週目の尿中アミノ酸排泄の変動について検討した。それによって,胎児のアミノ酸利用について考察し,これらの知見をもとに,妊娠中及び帝王切開分娩後の食事について検討する基礎的データの提供を目的とした。帝王切開による出産直後の総必須アミノ酸,特に塩基性アミノ酸(リジン,アルギニン),核酸塩基代謝産物(β-アラニン,β-アミノイソ酪酸),イソロイシン,ロイシン,システイン,プロリン及びリジンの代謝産物であるα-アミノアジピン酸が妊娠中の排泄量より有意な増加が認められたが,総非必須アミノ酸は増加よりむしろ減少を示した。すなわち,同じ肉体的ストレスでも,絶食によるストレスの場合に必要なのは糖新生に必要な非必須アミノ酸であるのに対して,妊娠によるストレスの場合に必要なのは必須アミノ酸であり,その中でも帝王切開直後に著しく増加した塩基性アミノ酸は染色体(DNA+塩基性タンパク質)合成に必要なアミノ酸で,胎児で細胞分裂が盛んに行われていることを示唆している。一方,β-アラニン,β-アミノイソ酪酸,α-アミノアジピン酸の増加は核酸塩基(ピリミジン)及びリジンが,帝王切開により児で利用されなくなり,血中に増加したため,母体肝臓での代謝が促進された結果と思われる。シスチンやプロリンも同じように胎児に利用されなくなったが,肝臓で代謝されることなくそのまま排泄されたものと考えられる。スレオニンやヒスチジンに関しては,以前から妊娠中は,尿中排泄量が異常に高くなることは報告されているが,今回もそのことは確認された。","subitem_description_type":"Other"}]},"item_1_description_12":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"Numerous reports have investigated quantitative changes of amino acids in urine during normal pregnancy, whereas none have focused on quantitative changes of amino acids in urine immediately after birth, especially by Caesarean section. This study investigated the quantitative changes of amino acids in urine immediately after Caesarian birth. The results showed that the daily quantities of total essential amino acids, basic amino acids (lysine and arginine), metabolites of pyrimidine bases in nucleic acids (β-alanine, β-aminoisobutyric acid), essential amino acids (isoleucine and leucine), non-essential amino acids (cystine and proline) and metabolite of lysine (α-aminoadipic acid) in urine increased significantly immediately after Caesarian birth. These results indicate that the stress in pregnancy required more essential amino acids than non-essential amino acids for the fetus, while the stress in starvation required more non-essential amino acids than essential amino acids for gluconeogenesis in liver.","subitem_description_type":"Other"}]},"item_1_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA11530249","subitem_source_identifier_type":"NCID"}]},"item_1_text_10":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Miyazaki Prefectural Nursing University"},{"subitem_text_language":"en","subitem_text_value":"Miyazaki Prefectural Nursing University"}]},"item_1_text_2":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_text_value":"短報"}]},"item_1_text_3":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Short Communication"}]},"item_1_text_9":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"宮崎県立看護大学"},{"subitem_text_value":"宮崎県立看護大学"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2005-03-01"}],"displaytype":"detail","filename":"KJ00004386388.pdf","filesize":[{"value":"994.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"url":"https://mpu.repo.nii.ac.jp/record/318/files/KJ00004386388.pdf"},"version_id":"a22bde94-954a-4238-a839-6a34b123aa7d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"尿中アミノ酸","subitem_subject_scheme":"Other"},{"subitem_subject":"妊娠","subitem_subject_scheme":"Other"},{"subitem_subject":"帝王切開出産","subitem_subject_scheme":"Other"},{"subitem_subject":"ストレス","subitem_subject_scheme":"Other"},{"subitem_subject":"人間","subitem_subject_scheme":"Other"},{"subitem_subject":"Amino acids in urine","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Pregnancy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Caesarean birth","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Stress","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Humans","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"妊娠30週目,帝王切開後1週目,5週目及び10週目の尿中アミノ酸の量的変動の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"妊娠30週目,帝王切開後1週目,5週目及び10週目の尿中アミノ酸の量的変動の検討"},{"subitem_title":"Studies of Quantitative Changes of Amino Acids in Urine during the Thirty Weeks Pregnancy, the First, Fifth and Tenth Weeks after Birth by Caesarean Section","subitem_title_language":"en"}]},"item_type_id":"1","owner":"3","path":["49"],"pubdate":{"attribute_name":"公開日","attribute_value":"2005-03-01"},"publish_date":"2005-03-01","publish_status":"0","recid":"318","relation_version_is_last":true,"title":["妊娠30週目,帝王切開後1週目,5週目及び10週目の尿中アミノ酸の量的変動の検討"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T07:37:26.983462+00:00"}